Thursday, November 1, 2018 |
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SCIENTIFIC INFORMATION |
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7:00am - 8:00am |
EARLY BIRD SESSIONSGenomics of Pediatric AML and MDSJeffery Klco, MD, PhD, St Jude Children's Research Hospital, Memphis, TN, USA |
1:00pm - 2:30pm |
CONCURRENT WORKSHOPSMolecular Tumor BoardElizabeth Swisher, MD, University of Washington, Seattle, WA, USA Stephen Lincoln, Invitae, San Francisco, CA, USA Eric H. Bernicker, MD, Houston Methodist Hospital, Houston, TX, USA Valentina Nardi, Massachusetts General Hospital, Boston, MA, USA Jonathan A. Nowak, MD, PhD, Brigham and Women's Hospital, Boston, MA, USA Angela Jacobson, MS, University of Washington, Seattle, WA, USA |
4:15pm - 5:45pm |
PLENARY SESSIONSomatic and Germline Mutations in Hematologic MalignanciesSpliceosome Gene Mutations in MDS Inherited Hematopoietic Malignancies |
7:30pm - 8:30pm |
Special Event: Emerging Targets for the Diagnosis of Cancer: NTRK Fusion in Solid Tumors |
Friday, November 2, 2018 |
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SCIENTIFIC INFORMATION |
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7:00am - 8:00am |
EARLY BIRD SESSIONSKeys to Publishing in Scientific JournalsBarbara A. Zehnbauer, PhD, Emory University School of Medicine, Atlanta, GA, USA Case Studies in Solid TumorCirculating Tumor DNA (ctDNA) Detection in CSF in a Patient with Metastatic Melanoma to the CNS An Unusual Driver Mutation in a Lung Adenocarcinoma LMNA/NTRK1 Fusion in a Paravertebral Soft Tissue Mass Recurrent Glioblastoma with Primary and Secondary Features in a Patient with a Deficiency of Mismatch Repair |
8:15am - 9:45am |
PLENARY SESSIONTumoral Genomic DiversityPredictor of Response to PARP Inhibitors Leveraging Personalized Medicine for Diagnosis and Treatment of Pancreatic Cancer |
10:45am - 11:45am |
CONCURRENT WORKSHOPS:Platform Presentations of Selected Abstracts Abstracts are selected by the Program Committee Platform Presentations of Selected Hematopathology AbstractsH025 - Ultradeep Error Corrected Next-generation Sequencing (NGS) of ABL1 Kinase Domain Mutations in BCR-ABL1 Positive Malignancies H041 - Longitudinal Monitoring of AML Tumors with High-throughput Single-Cell DNA Sequencing Reveals Rare Clones Prognostic for Disease Progression and Therapy Response H014 - Mate Pair Sequencing: Ushering Cytogenetics Into the Era of Personalized Medicine H039 - Donor-derived Clonal Hematopoiesis of Indeterminant Potential Mutations are Detected in Transplant Recipients after Allogeneic Hematopoietic Stem Cell Transplant Platform Presentations of Selected Solid Tumors AbstractsST002 - Analysis of Urinary Cell-free DNA for Early Detection and Surveillance of Bladder Cancer ST055 - DNA Sequencing of Human, Epstein-Barr Virus, and Helicobacter Pylori Genomes to Classify and Monitor Gastric Adenocarcinoma ST107 - Clinical Validation of MSK-ACCESS: An Ultrasensitive Next-generation Sequencing Assay for Liquid Biopsies in the Clinic ST144 - Prognosis Determined by Tumor Mutational Burden (TMB) Using Whole Exome Sequencing (WES) |
3:30pm - 5:00pm |
CONCURRENT SYMPOSIAUtilization of CRISPR/Cas Technique as Anti-Viral Therapeutic Agent and as an Adaptive Immune Modulator in DNA Editing and RNA TargetingCRISPR/Cas9 Targeting and Inactivation of Viral DNA Genomes Programmable RNA-targeting CRISPR-Cas Enzymes for RNA Detection and Therapeutics |
Saturday, November 3, 2018 |
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SCIENTIFIC INFORMATION |
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7:00am - 8:00am |
EARLY BIRD SESSIONSAMP Guidance for Non-standard or Emerging NGS Applications: Liquid BiopsyChristina Lockwood, PhD, University of Washington, Seattle, WA, USA Christopher D. Gocke, MD, Johns Hopkins University, Baltimore, MD, USA |
10:45am - 12:15pm |
WORKSHOPSClinical Implementation of Liquid Biopsy for Cancer PatientsClinical Applications of Digital PCR Liquid Biopsy for Solid Tumors: Promises and Perils
Mark Routbort, MD, PhD, University of Texas MD Anderson Cancer Center, Houston, TX, USA |
1:30pm - 3:00pm |
CONCURRENT SYMPOSIAFinding the Patient Perspective: Molecular Testing in Advanced NSCLC(Developed through a partnership between Medscape and the Association for Molecular Pathology)
Eric H. Bernicker MD, Houston Methodist Hospital, Houston, TX, USA Christina Lockwood, PhD, University of Washington, Seattle, WA, USA Lynette M. Sholl, MD, Brigham & Women's Hospital, Boston, MA, USA USA Don Stranathan, Lung Cancer Survivor/Advocate, Santa Rosa, CA, USA Precision Medicine in Mature Lymphoid MalignanciesResistance to Targeted Therapies in Chronic Lymphocytic Leukemia Towards a Genomic Classification of T Cell Malignancies: Opportunities for Precision Medicine
Megan S. Lim, MD, PhD, University of Pennsylvania, Philadelphia, PA, USA |
3:15pm - 4:45pm |
PLENARY SESSIONHypermutation and Mutation Signature Detection in CancerClinical Implications of Mutational Load and Signatures on Replication Repair Deficiency in Cancer Hypermutation in Cancer: Burden and Signatures of Mutational Processes |