Program

Thank you for your interest in the AMP 2018 Annual Meeting & Expo!

The AMP 2018 Program Committee has been working hard to plan a comprehensive program. We hope to connect you to the theme of "Precision Medicine Starts Here" by incorporating topics below into the Program in order to encourage dialogue and foster discussion amongst all attendees.

Topics:

  • Liquid Biopsies in Clinical Practice
  • Factors that Affect Immunotherapies
  • Emerging Technologies in Diagnostics: CRISPR, AI/Deep Learning Software, Single Cell DNA and RNA Sequencing, and More
  • Novel Biomarkers and Its Role in Disease and Therapy
  • Microbiome and Human Health
  • Next-generation Sequencing: Dealing with Challenging Regions, Clinical Advances, and Educational Sessions
  • Dealing with Big Data
  • Molecular Diagnostics Case Studies

 

Please see below the preliminary Program. Be sure to check back for updated Program information often!

Wednesday, October 31, 2018

GENERAL INFORMATION

7:00am - 5:00pm

Attendee, Speaker, and Exhibitor Registration and Check-In

7:30am - 5:00pm

AMP Committee Meetings (Invitation Only)

8:00am - 5:00pm

Corporate Workshop Day (No Registration Required!)

8:30am - 3:45pm

Molecular Pathology Outreach Course (MPOC)

(Separate Registration)

4:45pm - 5:45pm

Volunteer Appreciation Reception (Invitation Only)

 

Thursday, November 1, 2018

GENERAL INFORMATION

6:30am - 8:00am

Poster Set-Up

6:45am - 5:00pm

Attendee, Speaker, and Exhibitor Registration and Check-In

11:30am - 4:30pm

Exhibit Hall Open

5:45pm - 7:00pm

Welcome Reception (In the Exhibit Hall)

7:00am - 8:00am

Continental Breakfast

SCIENTIFIC INFORMATION

7:00am - 8:00am

EARLY BIRD SESSIONS

Genomics of Pediatric AML and MDS

Jeffery Klco, MD, PhD, St Jude Children's Research Hospital, Memphis, TN, USA

Finding the "Indel" in the Haystack

Large Indel Detection in Clinical NGS Assays
Sabah Kadri, PhD, University of Chicago, Chicago, IL, USA

Personalized Genomics: Advancing Continuity in Research to Clinical Care

Vincent Magrini, PhD, Nationwide Children's Hospital, Columbus, OH, USA
Catherine E. Cottrell PhD PhD, Nationwide Children's Hospital, Columbus, OH, USA

Lab of the Future: Cool Toys for the Diagnosis of Infectious Diseases

Validation of a Microbial Cell-free DNA Sequencing Test for Infectious Disease
Timothy A. Blauwkamp, PhD, Karius, Inc., Redwood City, CA, USA

Digital Universal High-Resolution Melt to Identify Individual Bacteria in Blood as an Approach to Diagnosing Sepsis
Stephanie I. Fraley, PhD, University of California, San Diego, CA, USA

Presentation of Selected Case Studies

8:00am - 8:15am

Break

8:15am - 8:30am

Opening Remarks

Lynne V. Abruzzo MD, PhD
Ohio State University Medical Center, Columbus, OH, USA and 2018 Program Chair

8:30am - 9:45am

AMP Award for Excellence in Molecular Diagnostics: Presentation and Lecture

Reimagining Healthcare: Next Generation DNA Sequencing to Ultrasound-on-a-Chip

Jonathan Rothberg, PhD, Yale School of Medicine, New Haven, CT, USA

9:45am -10:15am

Coffee Break

10:15am - 11:45am

PLENARY SESSION

Life Starts with DNA: Sequencing of the Baby Genome

Newborn Genomic Sequencing for Diagnosis and Screening
Jonathan S. Berg, MD, PhD, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA


Ingrid A. Holm, MD, PhD, Boston Children's Hospital/Harvard Medical School, Boston, MA, USA

11:45am - 1:00pm

General Lunch - Visit Exhibit Hall and View Posters

Networking Lunches

1:00pm - 2:30pm

CONCURRENT WORKSHOPS

Variant Interpretation: Challenges and Progress towards Solutions

What Variant Interpretation Among Laboratories (VITAL) Reveals
Elaine Lyon, PhD, ARUP Laboratories, Salt Lake City, UT, USA

ClinVar and ACMG Variant Classification Standards for Inherited Cardiovascular Disease

Birgit Funke, PhD, Veritas Genetics, Danvers, MA, USA
Harvard Medical School, Boston, MA, USA

Role of Next Generation Sequencing for Outbreak Investigation

Viral Genomics in the Clinical Lab
Alex Greninger, MD, PhD, University of Washington, Seattle, WA, USA

NGS for Natural Disasters
Randall Olsen, MD, PhD, Houston Methodist Hospital and Research Institute, Houston, TX, USA

Cutting Edge Informatics Infrastructure for Personalized Medicine

Innovative Computer Infrastructure for Clinical Bioinformatics
Elaine Gee, PhD, BigHead Analytics Group, Windsor, CA, USA

Economic Affairs Sponsored Session

Molecular Tumor Board

Elizabeth Swisher, MD, University of Washington, Seattle, WA, USA

Stephen Lincoln, Invitae, San Francisco, CA, USA

Eric H. Bernicker, MD, Houston Methodist Hospital, Houston, TX, USA

Valentina Nardi, Massachusetts General Hospital, Boston, MA, USA

2:30pm - 4:15pm

Coffee Break - Visit Exhibit Hall and View Posters

4:15pm - 5:45pm

PLENARY SESSION

Somatic and Germline Mutations in Hematologic Malignancies

Spliceosome Gene Mutations in MDS
Matthew Walter, MD, Washington University, St. Louis, MO, USA

Inherited Hematopoietic Malignancies
Lucy A. Godley, The University of Chicago, Chicago, IL, USA

SPECIAL SESSION: INFECTIOUS DISEASES

Meningitis/Encephalitis Syndromic Testing in the Clinical Setting: Is it Ready for Prime Time?

Are Meningitis/Encephalitis Panels Ready for Prime Time?
Kevin Alby, PhD, University of Pennsylvania, Philadelphia, PA, USA

Point-Counterpoint: Molecular Diagnosis of Meningitis/Encephalitis
Jennifer Dien Bard, PhD, Children's Hospital/University of Southern California, Los Angeles, CA, USA

5:45pm - 7:00pm

Welcome Reception (In the Exhibit Hall)

 

Friday, November 2, 2018

GENERAL INFORMATION

6:45am - 5:00pm

Attendee, Speaker, and Exhibitor Registration and Check-In

9:00am - 4:00pm

Exhibit Hall Open

7:00am - 8:00am

Continental Breakfast

SCIENTIFIC INFORMATION

7:00am - 8:00am

EARLY BIRD SESSIONS

Keys to Publishing in Scientific Journals

Barbara A. Zehnbauer, PhD, Emory University School of Medicine, Atlanta, GA, USA

Conceptual Nuts and Bolts of Visualizing Big Data in Genomics

Visualizations for Genomic Data, the GTEx Experience
Jared L. Nedzel, Broad Institute, Cambridge, MA, USA
Katherine Huang, Broad Institute, Cambridge, MA, USA

Professional Relations Committee Sponsored Session

AMP Guidance/Standards for NGS Germline Variant Confirmation

Case Studies in Solid Tumor

8:00am - 9:00am

SPECIAL SESSION: INFECTIOUS DISEASES

The Role of Genomic Susceptibility Testing in Predicting Antimicrobial Responses

Use of Molecular Testing to Predict Gonorrhea Treatment
Jeffrey D. Klausner, MD, PhD, University of California, Los Angeles, CA, USA

Value of Molecular AST Methods for Bacteria: Are We There?
Romney M. Humphries, PhD, Accelerate Diagnostics, Tucson, AZ, USA

8:00am - 8:15am

Break

8:15am - 9:45am

PLENARY SESSION

Tumoral Genomic Diversity

Predictor of Response to PARP Inhibitors
Elizabeth M. Swisher, MD, University of Washington, Seattle, WA, USA


Brian Wolpin, MD, MPH, Dana-Farber Cancer Institute, Boston, MA, USA

9:45am - 10:45am

Coffee Break - Visit Exhibit Hall and View Posters

10:45am - 11:45am

CONCURRENT WORKSHOPS:

Platform Presentations of Selected Abstracts

Abstracts are selected by the Program Committee

Platform Presentations of Selected Genetics Abstracts

Platform Presentations of Selected Hematopathology Abstracts

Platform Presentations of Selected Infectious Diseases Abstracts

Platform Presentations of Selected Informatics Abstracts

Platform Presentations of Selected Solid Tumors Abstracts

11:45am - 1:00pm

General Lunch - Visit Exhibit Hall and View Posters

1:00pm - 2:30pm

PLENARY SESSION

Microbiome and Predictive Response to Immunotherapy

Microbiome Changes with Infectious Complications During Stem Cell Transplantation
Ying Taur, MD, MPH, Memorial Sloan Kettering Cancer Center, New York, NY, USA

The Intestinal Virome: From Chronic Inflammation to Bacteriophage Therapy Targeting Multidrug Resistant Bacteria
Breck A. Duerkop, PhD, University of Colorado School of Medicine, Aurora, CO, USA

2:30pm - 3:30pm

Coffee Break - Visit Exhibit Hall and View Posters

(Even-numbered posters Attended)

3:30pm - 5:00pm

CONCURRENT SYMPOSIA

Utilization of CRISPR/Cas Technique as Anti-Viral Therapeutic Agent and as an Adaptive Immune Modulator in DNA Editing and RNA Targeting

CRISPR/Cas9 Targeting and Inactivation of Viral DNA Genomes
Bryan R. Cullen, PhD, Duke University Medical Center, Durham, NC, USA


Mitchell R. O'Connell, PhD, University of Rochester, Rochester, NY, USA

Clinical Advances in NGS

Robert L. Nussbaum, MD, Invitae Corporation, San Francisco, CA, USA

Wayne W. Grody, MD, PhD, University of California, Los Angeles, CA, USA

Insilico Sequencing Data and Tools: Current and Future Applications in Clinical Practice

"In Silico" Proficiency Testing
John D. Pfeifer, MD, PhD, Washington University School of Medicine, St. Louis, MO, USA

In Silico Proficiency Testing for Clinical Next Generation Sequencing
Karl V. Voelkerding, MD, University of Utah School of Medicine, Salt Lake City, UT, USA

4:15pm - 5:00pm

SPECIAL SESSION: INFECTIOUS DISEASES

ID Town Hall Meeting

5:00pm - 5:15pm

Break

5:15pm - 6:30pm

Business Meeting and Awards Session

(Open to All Registered Attendees)

7:00pm - 10:30pm

AMP 2018 Social Event (Separate Registration)

 

 

Saturday, November 3, 2018

GENERAL INFORMATION

6:45am - 2:00pm

Attendee, Speaker, and Exhibitor Registration and Check-In

9:00am - 1:30pm

Exhibit Hall Open

12:30pm - 1:30pm

Poster Removal

7:00am - 8:00am

Continental Breakfast

SCIENTIFIC INFORMATION

7:00am - 8:00am

EARLY BIRD SESSIONS

AMP Guidance for Non-standard or Emerging NGS Applications: Liquid Biopsy

Prior's Puzzlers

Thomas W. Prior, PhD, Case Western Reserve University, Cleveland, OH, USA

Strength in Numbers: Building an Academic Consortium to Facilitate Cost-Effective Clinical NGS

Jeremy Segal, MD, PhD, University of Chicago, Chicago, IL, USA

Presentation of Selected Case Studies

Platform Presentation of Selected Technical Topics Abstracts

 

8:00am - 9:00am

SPECIAL SESSION: INFECTIOUS DISEASES & MOLECULAR ONCOLOGY

Test Utilization and Clinical Utility of Molecular Test

Opportunities and Challenges in Laboratory Stewardship: Leaders Apply Here
Gary Procop, MD, Cleveland Clinic, Cleveland, OH, USA

8:00am - 8:15am

Break

8:15am - 9:45am

PLENARY SESSION

Artificial Intelligence in Genomic Medicine

Artificial Intelligence in Cancer Genomics and Therapy
Olivier Elemento, PhD, Weill Cornell Medicine - Englander Institute for Precision Medicine, New York, NY, USA

Cancer Genomics Visualization across Scales: Nucleotides to Cohorts
Nils Gehlenborg, PhD, Harvard Medical School, Boston, MA, USA

9:45am - 10:45am

Coffee Break - Visit Exhibit Hall and View Posters

(Odd-numbered posters Attended)

10:45am - 12:15pm

WORKSHOPS

Clinical Implementation of Liquid Biopsy for Cancer Patients

Clinical Applications of Digital PCR
Maria Arcila, MD, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Liquid Biopsy for Solid Tumors: Promises and Perils

Mark Routbort, MD, PhD, University of Texas MD Anderson Cancer Center, Houston, TX, USA

Show Me the Data: Visualization At the Interface of Molecular Pathology and Patient Care

Data Commons for Precision Cancer Medicine
Ethan Cerami, PhD, Dana-Farber Cancer Institute, Boston, MA, USA

Enterovirus D68 and Acute Flaccid Myelitis: What We've Learned Since 2014

The Role of Enterovirus D68 in Acute Flaccid Myelitis
Kevin Messacar, MD, University of Colorado/Children's Hospital Colorado, Aurora, CO, USA

Epidemiology, Surveillance, and Diagnosis of Enterovirus D68
Samuel Dominguez, MD, PhD, University of Colorado/Children's Hospital Colorado, Aurora, CO, USA

Training the Next Generations of Next Gen


Cecily P. Marroquin, American Board of Medical Genetics & Genomics, Bethesda, MD, USA

Fellowship Training and Continuing Certification in Molecular Pathology
Karen L. Kaul, MD, PhD, NorthShore University Health System, Evanston, IL, USA


Sarah P. Farrell, PhD

Best Practices for Clinical Validation of NGS Bioinformatics Pipeline

AMP Guidelines for Validating Next Generation Sequencing Bioinformatics Pipelines
Somak Roy, MD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

Alexis B. Carter, MD, Children's Healthcare of Atlanta, Atlanta, GA, USA

12:15pm - 1:30pm

General Lunch - Visit Exhibit Hall, and View Posters

1:30pm - 3:00pm

CONCURRENT SYMPOSIA

AMP Sponsored Session with Medscape NSCLC (Non-Small Cell Lung Cancer)

Precision Medicine in Mature Lymphoid Malignancies

Resistance to Targeted Therapies in Chronic Lymphocytic Leukemia
Jennifer A. Woyach, MD, The Ohio State University, Columbus, OH, USA

Towards a Genomic Classification of T Cell Malignancies: Opportunities for Precision Medicine
Megan S. Lim, MD, PhD, University of Pennsylvania, Philadelphia, PA, USA

Metagenomic Characterization of Molecular Scientists

Christopher E. Mason, PhD, Weill Cornell Medicine, New York, NY, USA

3:00pm - 3:15pm

Break

3:15pm - 4:45pm

PLENARY SESSION

Hypermutation and Mutation Signature Detection in Cancer


Uri Tabori, MD, PhD, Hospital for Sick Children, Toronto, Ontario, Canada


Ahmet Zehir, PhD, Memorial Sloan Kettering Cancer Center, New York, NY, USA

4:45pm - 5:00pm

Closing Remarks

Lynne V. Abruzzo MD, PhD
Ohio State University Medical Center, Columbus, OH, USA and 2018 Program Chair