Molecular Methodologies & Technologies

Thursday, November 1, 2018


7:00am - 8:00am


Personalized Genomics: Advancing Continuity in Research to Clinical Care

Vincent Magrini, PhD, Institute for Genomic Medicine (IGM) at Nationwide Children's Hospital, Columbus, OH, USA
Catherine E. Cottrell PhD PhD, Nationwide Children's Hospital, Columbus, OH, USA

Lab of the Future: Cool Toys for the Diagnosis of Infectious Diseases

Validation of the Karius Microbial Cell-free DNA Sequencing Test for Infectious Disease
Timothy A. Blauwkamp, PhD, Karius, Inc., Redwood City, CA, USA

A Smart Diagnostic: Technology that Learned to Identify and Count Individual Bacteria in Blood
Stephanie I. Fraley, PhD, University of California, San Diego, CA, USA

1:00pm - 2:30pm


Molecular Tumor Board

Elizabeth Swisher, MD, University of Washington, Seattle, WA, USA

Stephen Lincoln, Invitae, San Francisco, CA, USA

Eric H. Bernicker, MD, Houston Methodist Hospital, Houston, TX, USA

Valentina Nardi, Massachusetts General Hospital, Boston, MA, USA

Jonathan A. Nowak, MD, PhD, Brigham and Women's Hospital, Boston, MA, USA

Angela Jacobson, MS, University of Washington, Seattle, WA, USA


Friday, November 2, 2018


7:00am - 8:00am


Keys to Publishing in Scientific Journals

Barbara A. Zehnbauer, PhD, Emory University School of Medicine, Atlanta, GA, USA

3:30pm - 5:00pm


Utilization of CRISPR/Cas Technique as Anti-Viral Therapeutic Agent and as an Adaptive Immune Modulator in DNA Editing and RNA Targeting

CRISPR/Cas9 Targeting and Inactivation of Viral DNA Genomes
Bryan R. Cullen, PhD, Duke University Medical Center, Durham, NC, USA

Programmable RNA-targeting CRISPR-Cas Enzymes for RNA Detection and Therapeutics
Mitchell R. O'Connell, PhD, University of Rochester, Rochester, NY, USA

Clinical Advances in NGS

Robert L. Nussbaum, MD, Invitae Corporation, San Francisco, CA, USA

Wayne W. Grody, MD, PhD, University of California, Los Angeles, CA, USA

Insilico Sequencing Data and Tools: Current and Future Applications in Clinical Practice

"In Silico" Proficiency Testing
John D. Pfeifer, MD, PhD, Washington University School of Medicine, St. Louis, MO, USA

In Silico Proficiency Testing for Clinical Next Generation Sequencing
Karl V. Voelkerding, MD, University of Utah School of Medicine, Salt Lake City, UT, USA


Saturday, November 3, 2018


7:00am - 8:00am


AMP Guidance for Non-standard or Emerging NGS Applications: Liquid Biopsy

Christina Lockwood, PhD, University of Washington, Seattle, WA, USA

Christopher D. Gocke, MD, Johns Hopkins University, Baltimore, MD, USA

Platform Presentation of Selected Technical Topics Abstracts

TT074 - Multi-Patient Longitudinal Monitoring of Cancer Mutations from Circulating DNA of Using Personalized Single Color Digital PCR Assays
Christina M. Bouwens, Stanford University, Stanford, CA, USA

TT059 - Cell-free DNA Allograft Rejection Monitoring Using Low-coverage Whole Genome Sequencing
Niklas Krumm, MD, PhD, University of Washington, Seattle, WA, USA

TT070 - Universal Design and Rapid PCR for Genotyping by High Resolution Melting
Jessica Houskeeper, MRes , University of Utah, Salt Lake City, UT, USA

TT046 - The NIH Genetic Testing Registry (GTR): Test Methodologies as a Sensor of the Precision Medicine Environment
Adriana Malheiro, MS, National Center for Biotechnology Information, NIH, Bethesda, MD, USA

10:45am - 12:15pm


Clinical Implementation of Liquid Biopsy for Cancer Patients

Clinical Applications of Digital PCR
Maria Arcila, MD, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Liquid Biopsy for Solid Tumors: Promises and Perils

Mark Routbort, MD, PhD, University of Texas MD Anderson Cancer Center, Houston, TX, USA

1:30pm - 3:00pm


Metagenomic Characterization of Molecular Scientists

Christopher E. Mason, PhD, Weill Cornell Medicine, New York, NY, USA